Research Journal of Chemistry

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Multicomponent one pot synthesis of Substituted 3,4-Dihydropyrimidin-2-(1H)-ones by Nanocrystalline CeO2

Patil Vishvanath D., Salve Amruta M., Gharat V.D. and Gawand N.

Res. J. Chem. Environ; Vol. 25(8); 83-89; doi: https://doi.org/10.25303/258rjce8389; (2021)

Abstract
One of the most prominent multicomponent reactions (MCRs), Biginelli reaction has been utilized for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones catalyzed one-pot condensation of aldehyde, β- ketoester and urea in presence of ethanol. The present study deals with synthesis of biologically active 3, 4- dihydropyrimidin-2(1H)-ones using nano crystalline CeO2.