Review Paper:
Recent Designed
Simple Synthesis Approaches, Surface Modification Superparamagnetic Iron Oxide Nanoparticles
and Biologically Inspired Biocompatible Nanoparticles for Biomedical Applications
Kumar Hemant, Pandey Shwetank Shashi, Kumar Jitender, Kumar Pramod and Pani Balaram
Res. J. Chem. Environ; Vol. 26(12); 154-163;
doi: https://doi.org/10.25303/2612rjce1540163; (2022)
Abstract
In biomedical applications, iron oxide nanoparticles (IO NPs) offer several excellent
advantages. In biological systems, iron oxide nanoparticles have a non-toxic nature.
Iron oxide nanoparticles may be employed in a variety of biological applications
since they have magnetic and semiconductor characteristics. In order to get over
current limitations, recent research has focused on developing next-generation nanoparticle
systems with enhanced surface modifications for internalization and targeting. Superparamagnetic
iron oxide nanoparticles (MNPs) have a variety of biological applications, including
cell separation, hyperthermia, tissue healing and magnetic resonance imaging contrast
enhancement. This review clarifies how IO NPs are used in many biological applications.
According to this review, iron oxide plays a positive function in biological activity
because of its simplicity of synthesis, various magnetic behaviors, biocompatibility
and biodegradability. When iron oxide nanoparticles are used in a biological way,
their size, shape, surface modification, aggregation and electrical properties all
have a unique effect. Based on this review work, the IO NPs may be specified for
biocompatibility, hyperthermia, drug delivery, magnetic resonance imaging, tissue
repair and magnetofection.
