Review Paper:
The genomic effects
of radiation exposure: induction of cancers and genetic aberrations in mammalian
cells
Garg Pankaj
Res. J. Chem. Environ; Vol. 27(9); 112-122;
doi: https://doi.org/10.25303/2709rjce1120122; (2023)
Abstract
Radiation exposure can be a two-edged sword. On one hand, the deployment of radiotherapy
is one of the most acceptable modalities for malignancy treatment, for the reason
of its ability to kill cancer cells. Equally, one is scared of the exposure to man-made
emissions in the form of nuclear disasters or related to any form of hilarious power
generation during the war. It is rational to facilitate the body enduring small
intensity of emissions without any marked side effects. However, there are countless
detrimental side effects of being exposed to elevated levels of radiation. These
harmful side effects form an underlying fear in the general public in understanding
the actual mechanism and concrete remediation of radiation exposure.
The present study investigates in detail the principles of radiation safety and
how different types of radiation emissions affect the human body when exposed at
different levels of their intensity. Furthermore, it is also conferred how cellular
mutations are originated in different organs and body systems due to different levels
of radiation exposure and also the potential of organisms to develop resistance
(threshold limit) to counteract harmful effects of radiation.