Study of Carboxyhemoglobin
Levels of Patients of Respiratory Viral Infections: An important clinical indicator
of severity
Singh Neha, Angel Annette, Joshi Vinod, Angel Bennet and Sharma Bhawna
Res. J. Biotech.; Vol. 20(8); 197-203;
doi: https://doi.org/10.25303/208rjbt1970203; (2025)
Abstract
Respiratory viral infections are the common and frequent infections affecting humans
throughout the year. As these viral pathogens in majority of cases of persistent
infections reach the lungs, their intracellular replication in pulmonary cells can
lead to interfere the composition of haemoglobin molecule by means of liberating
carbon monoxide as metabolic and catabolic products of virus replication. The blood
samples of patients admitted in the Sharda Hospital, U.P. with respiratory distress
like condition were taken for the study. The serum was separated and the carboxyhemoglobin
levels were analysed employing ELISA technique as per the manufacture protocol.
Present study reports carboxyhemoglobin level in 59 patients in terms of ng/ml of
blood. Since these levels have been observed in case of COPD (Chronic Obstructive
Pulmonary Distress) indoor patients, the reported values could serve as cut off
levels of carboxyhemoglobin in severe patients of COPD.
