Review Paper:
Nanotechnology:
A Way for Active Targeting of Cancer Cells
Sharma Rama
Res. J. Biotech.; Vol. 20(2); 222-227;
doi: https://doi.org/10.25303/202rjbt2220227; (2025)
Abstract
Since cancer is one of the top causes of death, researchers have been working hard
for cancer management. Creating drugs that can be utilized for both early detection
and efficient treatment, is one of the most challenging parts of cancer treatment.
Traditional cancer treatment is linked with a high risk of serious chemotherapeutic
side effects and occasionally lacks precise technology for early tumour identification.
It was thought that a medication that could serve as a "magic bullet" and could
only recognize cancer cells, was required for better therapeutic ratio, defined
as the distinction between how treatment impacts cancer cells against healthy tissues.
Nanoparticle systems provide numerous potentially efficient approaches for developing
customized cancer detection and treatment medications. There are two methods for
targeting nanoparticles: passive targeting and active targeting. Nanoparticles can
be effectively localized inside the tumour microenvironment with passive targeting.
Due to their active targeting, nanoparticles can be actively taken up by tumour
cells.
