Assessment of
Hematological and Hormonal levels of PCOS subjects: a case-control study
Kannan Pavithra, Ramachandran Chandirasekar, Venkatachalam Uthayakumar, Selvam Ganapathy
and Chandran Vijayan
Res. J. Biotech.; Vol. 20(7); 108-113;
doi: https://doi.org/10.25303/207rjbt1080113; (2025)
Abstract
Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders
in reproductive-aged women. PCOS is considered to be a complex disease that affects
childbearing age, adolescents and postmenopausal women. A significant number of
cases were found in and around Tamil Nadu. The study recruited 65 (PCOS subjects)
experimental and 65 age-matched controls (±5 years). Again, they were classified
into three groups (Group I, II and III) based on age duration. The hematological
and hormonal activities were analysed using laboratory technique. Epidemiological
data were documented in clinical records including acne, hirsutism, irregular periods
and obesity (BMI).
Obesity, irregular periods, hirsutism and oily skin type were observed. Among the
findings, higher BMI level 30%, irregular periods 46%, hirsutism 10% and oily skin
type 40% were found in PCOS. The mean level of hematological parameters appears
to be insignificant compared to PCOS and controls. FSH and LH hormone levels were
estimated. FSH and LH levels were significantly elevated in PCOS subjects. The findings
of the study indicate that no associations were found in the hematological parameters
but a larger sample size is required for future studies.
