Biogenic Synthesis
of ZnO Nanoparticles from Corollocarpus epigaeus: Phytochemical Characterization
and Antimicrobial Applications
Soundravalli V. and Kalaiarasi Kalamegam
Res. J. Biotech.; Vol. 20(7); 142-149;
doi: https://doi.org/10.25303/207rjbt1420149; (2025)
Abstract
In recent days, nanotechnology incorporates into the medical field that enhances
the benefits in drug delivery system. Corallocarpus epigaeus, a tendril, has the
number of medicinal properties for diabetes, rheumatism, herpes and for snake bites23.
In this study, the tuber of this plant was dried and extracted to identify its phytoconstituents
qualitatively showing the presence of flavonoids, terpenoids and steroids. The synthesis
of nanoparticles using zinc sulphate has widespread use in biomedicine due to its
small size. The UV – spectroscopy of ZnONPs showed the peak at 412 nm, 573 nm and
600 nm. and FTIR results explained the peak absorbed at 1637 cm-1, 1412 cm- 1, 708
cm-1 and 612cm-1 indicating the presence of functional groups such as hydroxyl amine,
alkenes, alkynes, aliphatic amines, carboxylic acids, alkyl halides and aromatic
compounds.
The SEM analysis also showed the clear picture of the presence of ZnONPs in spherical
shape. The study was further investigated for antimicrobial properties of E.coli
(13 mm), Pseudomonas species (16 mm), Klebsiella species (12 mm) and Staphylococcus
species (20 mm) at 80 μg/ml of ZnONPs of Corollocarpus epigaeus. The sensitivity
is higher in ZnONPs than in the methanol and aqueous plant extract.
