Research Journal of Biotechnology

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Review Paper:

Unveiling the Heat-Loving Microheroes - A Deep Dive into the World of Thermophilic Bacteria: A Review

Shakya Poonam, Nayak Anju, Rai Ajay, Singh R.P. and Garg Akshay

Res. J. Biotech.; Vol. 20(6); 165-174; doi: https://doi.org/10.25303/206rjbt1650174; (2025)

Abstract
Thermophilic bacteria thrive in environments exceeding 70°C, from hot springs to terrestrial oil reservoirs, they possess remarkable resilience and adaptability, making them unique in the microbial world. These heat-loving microorganisms exhibit high metabolic activity, enabling them to produce thermally stable enzymes that function optimally under extreme conditions. Such enzymes are highly valued in various industries including biotechnology, pharmaceuticals and environmental management where they offer more efficient and environmentally friendly processes compared to conventional methods.

The polymerase chain reaction (PCR) technique, essential in molecular biology, utilizes Taq polymerase from the thermophilic bacterium Thermus aquaticus. Additionally, thermophilic bacteria are being explored for applications in biofuel production, waste management and the food and beverage industry. Their ability to survive in extreme conditions also makes them important for studying the limits of life, potentially offering insights into the origins of life on the Earth and the possibilities of life beyond our planet.