Identification
of response regulator genes of Xanthomonas oryzae pv. oryzae involved in the c-di-GMP
signaling
Porwal Priyanshi and Pandey Alok
Res. J. Biotech.; Vol. 20(11); 128-131;
doi: https://doi.org/10.25303/2011rjbt1280131; (2025)
Abstract
Xanthomonas oryzae pv. oryzae (Xoo) is responsible for bacterial blight, a serious
and destructive rice disease. Xoo genome analysis has indicated that this pathogenic
bacterium encodes several proteins forming two-component signal transduction systems
(TCSTSs). Two proteins, a sensor kinase and a response regulator form a classical
TCSTS. Response regulators display a variety of functions including enzymatic activities.
The Cyclic-di-GMP (c-di-GMP) participates in the signaling pathway operative in
the members of Genus Xanthomonas. The present work aimed to identify the Xoo response
regulators putatively participating in the c-di-GMP signaling.
Proteins having HD-GYP and EAL domains display c-di-GMP phosphodiesterase activity
directed towards degradation of the c-di-GMP. Proteins having PleD (GGDEF) domain
act as di-guanylate cyclases that participate in the synthesis of c-di-GMP synthesis.
In silico analyses have been performed on the available genome of the BXO1 strain
of Xoo to identify response regulator genes having HD-GYP/EAL/GGDEF domains. The
present work has revealed the presence of several response regulator genes of Xoo
that might be controlling the c-di-GMP-dependent signaling.
