Review Paper:
Green-Synthesized
Nanoparticles of Catharanthus Roseus: A Review of Synthesis, Characterization and
Biomedical Applications
Sudhir P.K., Venkatesan Hariram and Vettrivel Arul
Res. J. Biotech.; Vol. 20(10); 345-351;
doi: https://doi.org/10.25303/2010rjbt3450351; (2025)
Abstract
Catharanthus roseus, a medicinal plant rich in bioactive compounds like alkaloids,
flavonoids and terpenoids, has gained prominence in green nanoparticle synthesis.
This review highlights its role as a reducing and stabilizing agent in the eco-friendly
production of nanoparticles such as silver (AgNPs), gold (AuNPs), zinc oxide (ZnO-NPs)
and iron oxide (Fe₂O₃-NPs). Characterization techniques including UV-Vis spectroscopy,
FTIR and SEM, confirm their stability and functionality. These nanoparticles demonstrate
significant biomedical applications including antimicrobial, antioxidant, anticancer
and anti-inflammatory activities.
AgNPs and ZnO-NPs exhibit strong pathogen disruption and oxidative stress reduction
while AuNPs show targeted cytotoxicity against cancer cells. Challenges such as
scalability and reproducibility persist, but interdisciplinary research and clinical
validation can unlock their full potential. This review underscores the promise
of C. roseus-derived nanoparticles in sustainable nanotechnology for health and
environmental solutions.
