Comparatie study
of rosmarinic acid content and antioxidant activity of four Lamiaceae species extracts
in Vietnam
Pham Thi My Tram and Pham Giang Que Anh
Res. J. Biotech.; Vol. 21(2); 224-229;
doi: https://doi.org/10.25303/212rjbt2240229; (2026)
Abstract
The Lamiaceae (formerly Labiatae), known as the mint family, is a popular herbal
plant in Vietnam and worldwide. This study aimed to compare the rosmarinic acid
content of four plant extracts from the Lamiaceae, including Elsholtzia ciliata
(Thunb.) Hyland., Mentha piperita L., Ocimum basilicum L., Plectranthus amboinicus
(Lour.) Spreng. Ground materials were extracted on a magnetic stirrer at 900C for
60 minutes. The filtered extracts were checked for quantitative phytochemical analysis,
rosmarinic acid content using a spectrophotometer and antioxidant activity. The
quantitative result showed that four Lamiaceae species extracts had a lot of polyphenols
(dark green precipitate) and flavonoids (yellow precipitate).
The rosmarinic acid content in four species was 4.87-15.42 mg/g DW. These results
also showed a strong correlation between rosmarinic acid concentration and IC50
value (r = -0.87) in which rosmarinic acid production and antioxidant activity of
Mentha piperita L. were highest. Our results suggest that Mentha piperita L. and
others may be a good source of rosmarinic acid, an antioxidant compound.
