Green Synthesis,
Characterization, Antimicrobial Potential and Cytotoxic Evaluation of Silver Nanoparticles
derived from Marine Seaweed Valonia Utricularis
Singh Gurinder, Sharma Asha, Chaudhary Narendra and Sharma Gaurav
Res. J. Biotech.; Vol. 21(2); 160-168;
doi: https://doi.org/10.25303/212rjbt1600168; (2026)
Abstract
Few studies have been conducted on the production of silver nanoparticles from marine
seaweeds using environmentally friendly green approach. In the current investigation,
aqueous extract of Valonia utricularis (green marine algae) was used to produce
silver nanoparticles and to assess their antimicrobial activity against clinically
important pathogens and in vitro cytotoxic effect against HCT116 and HeLa cell lines.
The effective synthesis and functionalization of the produced AgNPs were verified
by characterization using UV-visible spectroscopy, Fourier transform infrared spectroscopy
(FTIR), X-ray diffraction (XRD), SEM and TEM.
The biosynthesized AgNPs exhibited most potent antimicrobial protection against
clinically important Gram-positive, Gram-negative and fungal pathogens and remarkable
dose dependent cytotoxic effect against HCT116 and HeLa cell lines. In the future,
the above environment friendly AgNP synthesis process might be readily scaled up
to overcome the global challenge of multi drug resistance and treatment of cancer
to meet the industrial demand.
