Antioxidant, Anti-inflammatory
and Free radicals scavenging activity of methanolic extract of Musa paradisiaca
L peels
Kumar Ramesh, Kumar Sidhanshu, Rangwa Amit Kumar and Rawat Riya
Res. J. Biotech.; Vol. 21(1); 12-20;
doi: https://doi.org/10.25303/211rjbt012020; (2026)
Abstract
Musa paradisiaca commonly known as banana is grown and eaten as ripe fruit around
the world. Peels are a waste product that makes up roughly 18–33% of the entire
fruit. Banana peels have shown various biological properties. Therefore, the phytoconstituents,
antioxidant potentials, anti-inflammatory activities and free radical scavenging
properties of banana peels were identified in order to make use of them as a source
of useful components. The presence of alkaloids, flavanoids, proteins, carbohydrates,
tannins, terpenoid, saponins and glycosides is revealed by phytochemical analysis
of methanolic extracts of banana peel. While terpenoids and saponins have antibacterial
properties, alkaloids, flavanoids and tannins are phytochemicals with excellent
antioxidant qualities. There were 137.6 ± 39.59 mg GAE/g of total phenolic content
and 256.6 ± 29.30 mg QE/g of flavonoid content. At 1000 μg/ml conc., the methanolic
extract of Musa paradisiaca peels exhibited the maximum antioxidant activity which
was dose dependent.
Furthermore, ascorbic acid (the reference control) and the antioxidant activity
by peel extracts were comparable. To ascertain the scavenging capabilities of free
radicals, we assessed the scavenging activities of nitric oxide, superoxide and
hydroxyl radicals. The nitric oxide, superoxide and hydroxyl radical scavenging
capabilities were found to be dose dependant. According to the study's findings,
banana peel has anti-inflammatory properties at all doses. Thus, our results showed
that banana peels have the strongest in vitro antioxidant, anti-inflammatory and
free radical scavenging properties. However, extensive research is required to fully
understand its potential biomedical applications.
