Comprehensive
Characterisation and Potent Antibacterial Applications of Polymer-Capped Silver
Nanoparticles: A Green Synthesis
Oza Kalrav, Raj Praharsh, Makvana Chirag and Panchal Vikram
Res. J. Biotech.; Vol. 21(1); 224-231;
doi: https://doi.org/10.25303/211rjbt2240231; (2026)
Abstract
The distinctive antibacterial properties of silver nanoparticles (AgNPs) have attracted
a significant inquisitiveness, particularly in their environmentally friendly synthesis.
Using leaf extract of Swertia chirata plant as a reducing agent for the conversion
of Ag+ salt solution to AgNPs which was capped with polyvinylpyrrolidone (PVP),
this work offers a unique and environmentally beneficial method. PVP-functionalized
AgNPs were characterized by FTIR, UV-Vis spectroscopy, XRD and HR-TEM. The absorption
spectra of PVP-capped AgNPs displayed distinctive peaks at 457 nm, indicating the
stable formation of nanoparticles. FTIR analysis confirmed the successful synthesis
of PVP-AgNPs, while the X-ray diffraction pattern verified their cubic structure.
HR-TEM investigation showed spherical shape and homogeneous dispersion of PVP-AgNPs.
The average particle size of synthesised AgNPs was 11.32 nm and they were functionalised
with PVP to improve biological activity. The antibacterial activity of PVP-AgNPs
was evaluated against miscellaneous bacteriological strains such as S. aureus, P.
aeruginosa, GPB and E. coli showing efficacy against all of these bacterial strains.
