In silico and
antibacterial studies of Thiadiazole and Triazole linked 1,8-Napthyridine derivatives
Bhargavi Lakshmi J., Bhaskar Pittala, Laxminarayana Eppakayala, Paramesh Donta and
Chittireddy Venkata Ramana Reddy
Res. J. Chem. Environ.; Vol. 29(1); 46-51;
doi: https://doi.org/10.25303/291rjce046051; (2025)
Abstract
A series of thiadiazole and triazole linked 1,8-napthyridine derivatives were screened
for antibacterial activity and docking studies were performed. Compared to the tetracycline,
all these compounds have shown good to moderate antibacterial activity against Staphylococcus
aureus, Bacillus cereus, Micrococcus luteus, Klebsiella pneumonia, Salmonella paratyphi
A and Escherichia coli.
