A Preliminary
in vitro Investigation on the Crude Methanol Extract of Bacopa monnieri (L.) Pennell.
An Important Multi Medicinal Plant
Jonnada Prema Jose, Jaya Sri Puli, Sape Subba Tata and Barsingi Sudha Rani
Res. J. Chem. Environ.; Vol. 29(7); 73-77;
doi: https://doi.org/10.25303/297rjce073077; (2025)
Abstract
The present investigation is to study the B. monnieri crude methanol extract antibacterial
and anticancer activities. Crude methanol extract showed very positive antibacterial
activity on 6 different bacterial strains. Staphylococcus aureus has been identified
as more sensitive than the other strains (Staphylococcus aureus>Enterococcus faecalis>Bacillus
subtilis> Escherichia coli> Pseudomonas aeruginosa>Proteus vulgaris).
Further, the crude methanol extract exhibited a promising anticancer activity and
expressed considerable IC50 values (108.6 and 86.4μg/ml for MCF-7 and MDA-MB-231).
These observations suggest that the medicinal plant B. monnieri can be used in antibacterial
and anticancer studies.
