Inhibitory effect
of E.conferta mediated Silver nanoparticles against the infection causing pathogens
Rose C. Merlin and Sherine H. Benita
Res. J. Chem. Environ.; Vol. 29(7); 78-84;
doi: https://doi.org/10.25303/297rjce078084; (2025)
Abstract
This work explores green synthesis approach of producing silver nanoparticles (AgNPs)
from methanolic Elaeagnus conferta leaves extract. It emphasizes how naturally occurring
biomolecules from plant extracts might get utilized as active agents for producing
nanoparticles. Furthermore, the green-synthesised AgNPs' antibacterial effectiveness
against microorganisms that cause infection, was assessed, highlighting their capacity
to function as strong antimicrobials. The produced nanoparticles have been examined
employing several methods encompassing “energy dispersive X-ray analysis (EDX),
TEM (transmission electron microscopy), SEM (scanning electron microscopy), FTIR
(Fourier transform infrared spectroscopy), X-ray diffraction (XRD), as well as UV-visible
spectroscopy.
UV-visible spectroscopy as well as qualitative examination demonstrated the presence
of phytochemicals with medicinal significance including alkaloids, flavonoids, terpenoids,
phenolic compounds, as well as steroids. It was discovered that AgNPs mediated by
Elaeagnus conferta had mean crystalline size 26.59nm. EDAX analysis indicated that
elemental composition of nanoparticles consisted of 34.06% silver and 10.15% oxygen.
EC-AgNPs were tested against infection-causing pathogens like Candida albicans,
Staphylococcus aureus, Aspergillus niger, as well as Escherichia coli. Biosynthesized
EC-AgNPs exhibited significant inhibitory effects against all tested pathogens.
These findings conclude that EC-AgNPs have strong potential as effective antimicrobial
agents.
