Research Journal of Chemistry

and Environment


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Synthesis and antimicrobial studies of Quinoline-8-thioglycolic acid, Quinaldine-8-thioglycolic acid and their derivatives

Prakash Sachin, Gupta Anju K. and Prakash D.

Res. J. Chem. Environ.; Vol. 29(7); 85-91; doi: https://doi.org/10.25303/297rjce085091; (2025)

Abstract
Quinoline-8-thioglycolic acid, quinaldine-8-thioglycolic acid and their derivatives have been synthesized. All the newly prepared compounds were evaluated for their antibacterial activity against five bacterial strains viz. Staphylococcus aureus, Staphylococcus albus, Ps. pyocyanea, Proteus and Escherichia coli. Some transition metal chelates of Quinoline-8-thioglycolic acid and Quinaldine-8-thioglycolic acid were found to be active against pathogenic bacteria.