Exploring the
Biological and Theoretical Aspects of Rare Earth Metal Mixed Ligand Complexes: A
Synergistic Approach
Jani D.N., Jani D.H. and Paghadar N.A.
Res. J. Chem. Environ.; Vol. 29(10); 54-65;
doi: https://doi.org/10.25303/2910rjce054065; (2025)
Abstract
In order to create novel transition metal-based coordination compounds, Schiff bases
based on the sulpha drug reacted with various 2-hydroxy-benzaldehyde derivatives.
The antibacterial properties and spectroscopic attributes of the synthesized ligands
and their heterochelates were extensively examined. The structural characterization
of the ligands was accomplished through 1H-NMR, IR, Mass spectrometry, UV-Vis spectroscopy
and elemental analysis, while the heterochelates' structures were validated using
IR spectroscopy.
In vitro evaluations were conducted to assess the activity of the ligands and heterochelates
against Gram +ve bacteria (S. aureus, B. subtilis), Gram -ve bacteria (E. coli,
P. aeruginosa) and against fungi A. niger. The findings underscore the promising
nature of coordination compounds based on transition metals and highlight the necessity
of further exploration in this field.
