Macrocyclic Schiff
base Ligand and their Metal Complexes: Synthesis, characterization and biological
studies
Haj Hasan Manal, Al-khuder Mohammad Moudar and Alkhuder Omar
Res. J. Chem. Environ.; Vol. 29(10); 1-11;
doi: https://doi.org/10.25303/2910rjce01011; (2025)
Abstract
The synthesis of a new ligand, N4 Tetra (Methel Azometine)-Di Phenylen hydrazide
(TMADPH), was carried out by condensing 1,2-diacetylhydrazine with 1,4 -phenylendiamin
to obtain the ligand TMADPH. After confirming the structure of the bond using FT–IR,
UV–VIS, 1H–NMR and 13C–NMR, its metal complexes with Zr4+, Mn2+and Ni2+ were prepared
and studied using FT–IR, UV–VIS spectroscopy, electrical conductivity and metal
ratio analysis.
The results indicated that all the metal complexes had a mononuclear structure.
Furthermore, the biological activity against Pseudomonas aeruginosa and Staphylococcus
aureus bacteria was studied, revealing that the prepared metal complexes exhibited
greater biological activity than the macrocyclic ligand.
