Review Paper:
Applications of
Schiff Bases and their Metal Complexes in Catalytic Transformations
Gupta Akhilesh Kumar
Res. J. Chem. Environ.; Vol. 29(9); 190-210;
doi: https://doi.org/10.25303/299rjce1900210; (2025)
Abstract
Schiff base ligands can easily coordinate with metal ions and forms stable complexes,
which facilitate the utilization of Schiff base metal complexes as catalyst in organic
synthesis. Various routes for the synthesis and application of various Schiff base
metal complexes in the field of catalytic transformations to synthesize organic
compounds economically and more selectively are well-documented. Here we discuss
the synthesis of 2-Amino-3-cyano-4H-pyrans or 4H-chromenes, synthesis of polyhydroquinoline
derivatives by the Hantzsch reaction, Biginelli reaction, Suzuki–Miyaura and the
Sonogashira cross-coupling reactions, synthesis of tetrazoles, synthesis of β-hydroxy-1,2,3-triazole,
synthesis of N-aryl amines by Chan–Lam coupling, catalytic epoxidation of alkenes,
catalytic reduction of aromatic ketones into alcohol etc.
Numerous Schiff base complexes can withstand higher temperature that provides them
extra flexibility for their catalytic action even at higher temperature. Versatile
nature of Schiff base (SB) ligands also prompted researchers to focus on studying
catalytic activity where metal-SB immobilized on core-shell magnetic nanoparticles
as nanocatalyst. The catalytically active Schiff base metal complexes are prerequisite
to enhance the yields of stereospecific, regioselective and chemoselective products.
This review highlights the Schiff base metal complexes as a catalyst to complicated
organic synthesis into a simple one pot synthesis, thus may be beneficial to both
researchers and industries in the field of catalytic reaction.
